Tottenham Hotspur are facing a significant injury headache heading into the latest Premier League fixtures, with API-SPORTS data confirming multiple first-team absentees that will reshape the betting markets this week. With at least 8 distinct players confirmed as missing fixtures, Ange Postecoglou’s squad depth is being tested to its absolute limit — and the ripple effects on anytime goalscorer and top scorer odds are impossible to ignore.
Top Performers and Absentees to Know
The headline casualty is Dominic Solanke, ruled out with a sprained ankle — a blow that hits Spurs’ attacking output hardest. Solanke has been central to Tottenham’s build-up play since arriving from Bournemouth, and his absence directly opens up value bets in the anytime goalscorer market as Postecoglou scrambles for alternatives up front.
Dejan Kulusevski is also sidelined with a persistent jumper’s knee issue, a recurring problem that appears across multiple entries in this week’s injury data. Kulusevski has been one of Spurs’ most productive wide attackers this season — with his energy and pressing from the right flank a key weapon — making his absence a genuine tactical setback. Bettors tracking top scorer odds should take note: without both Solanke and Kulusevski in the lineup, Tottenham’s expected goals number drops considerably.
James Maddison is another notable absentee, listed with a jumper’s knee across multiple fixture entries. The playmaker’s creativity from deeper positions is often the catalyst for Spurs goals, and without him pulling the strings, the team’s ability to unlock deep blocks is severely compromised.
Defensively, Radu Drăgușin is also out with a knee injury, while Destiny Udogie misses out with a knee problem of his own, stripping Postecoglou of width on the left side. Add in Yves Bissouma (wound/injury), Manor Solomon (calf injury), Bryan Gil Salvatierra (outer ligament tear), and K. Takai (foot injury), and you have a picture of a squad stretched dangerously thin across every line.
Betting Context: What the Injury List Means for the Markets
When a team loses 3 or more key attackers and midfielders simultaneously, the immediate market reaction is typically a shift in the match result odds — expect bookmakers to lengthen Tottenham’s win probability for any upcoming fixture. Now is the time to compare odds across multiple sportsbooks before the lines fully adjust.
- Anytime goalscorer markets — With Solanke and Kulusevski both out, fringe forwards and second-string attackers step into the spotlight. Look for inflated odds on whoever starts in the No.9 role as a potential value bet.
- Top scorer odds — Solanke’s absence over multiple fixtures could cost him ground in the race for the Premier League golden boot. Rivals will likely see their top scorer odds shorten as bookmakers react to the news.
- Clean sheet and BTTS markets — Losing Udogie and Drăgușin defensively makes Spurs more vulnerable at the back. Both Teams to Score bets gain appeal in Tottenham’s upcoming matches.
- First goalscorer value bets — With the usual suspects unavailable, there may be best odds available on unexpected starters who are priced generously before lineups are confirmed.
What to Watch This Week
The sheer volume of absences — at least 8 confirmed individual players missing fixtures — makes Tottenham the most injury-disrupted side in the Premier League right now according to this week’s API-SPORTS data. Postecoglou will need to rely on youth and fringe options, which historically leads to unpredictable team performances and opens up handicap markets.
Smart bettors should monitor Thursday and Friday team news closely. If Solanke and Maddison are officially ruled out before kick-off, the anytime goalscorer market for Tottenham’s opponents becomes increasingly attractive. Cross-reference the latest injury updates with live odds movements — squads this depleted rarely outperform pre-match expectations.
Live football statistics powered by API-SPORTS. Compare current odds at OddsForge live odds.

